In the literature: October 2016

In the literature: October 2016

Correspondence to Professor Andres Cervantes; [email protected] MUTATIONAL SIGNATURES WITH POTENTIAL THERAPEUTIC INTEREST IN OESOPHAGEAL ADENOCARCINOMA A consortium on clinical and molecular stratification on oesophageal adenocarcinoma established in Britain has recently published in Nature Genetics, a whole-genomic sequencing analysis of more than 100 samples. Interestingly, they describe...

Helix: October 2016 issue

This issue contains a wide variety of articles covering new genes and mutations, unusual phenotypes, and a reminder that novel genetic technologies need to be paired with the appropriate mechanisms to inform patients of new results or annotations of DNA variants.

Cover vol. 13, no. 5, October 2016

In the literature: March 2016

Correspondence to Professor A Cervantes; [email protected] A BETTER UNDERSTANDING OF RESISTANCE TO ANTI-EGFRS IN NON-SMALL CELL LUNG CANCER The way clones resistant to anti-EGFR (Epidermal Growth Factor Receptor) inhibition evolve in non-small cell lung cancer is far from being determined. In an international cooperative effort led by investigators at Johns Hopkins Hospital in Baltimore, t...

In the literature: May 2016

Correspondence to A Cervantes; andres. [email protected] LOW-GRADE GLIOMAS ENJOY BETTER SURVIVAL WHEN CHEMOTHERAPY IS ADDED TO RADIATION Radiotherapy as single modality was considered the standard of care for low-grade gliomas, a mixed population of low proliferative tumours including oligodendrogliomas, oligoastrocytomas and grade 2 astrocytomas. However, a recently reported trial in the New Eng...